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Methotrexate and Running

4 watchers
Jan 2018
4:00pm, 7 Jan 2018
4557 posts
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Northern Exile
I also take methotrexate. It would be wrong to say I'm running as well as I did before arthritis blighted my life, but I still do it. I feel pretty crap for about 36 - 48 hours after I take it, though the severity of this is variable. Last week was awful.

My rheumy is switching me to injection, am told that it's more efficient and has less side effects so that has to be good thing.
Jan 2018
7:18am, 11 Jan 2018
61 posts
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daisyjess
Northern Exile, I switched to the injections about six months ago. I had the same problem with feeling like utter crap after taking the tablets. I don't have any problematic side effects with the injection.

I always take the injection after I've been for my run, as running makes the injection site a bit sore (only while running, and running is the only thing that does it - I think it's all that hard work my abs (ha) are doing.

Bit of a digression, but does anyone else find that methotrexate knocks them straight out for a nap? I was talking to someone else who takes it and she thought it was really weird - it stops her from sleeping.
Jan 2018
9:41am, 11 Jan 2018
4558 posts
  • 0
Northern Exile
It was methotrexate day yesterday, so as usual feel pretty dreadful today. I'm really looking forward to switching to injections, HAC are delivering the stuff on Friday and I have an appointment with the rheumy nurse on Tuesday to show me how to do it. Good advice re. doing it after a run, I'm thinking I'll probably do it on Weds eves as I swim on Weds mornings then go to work.

I don't find it affects my sleep. Steroids do!
27 Jul
10:17pm, 27 Jul 2020
1805 posts
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Pinkliverbird
Just came across this group by accident and although a couple of years old was wondering how everyone was getting on. I too am on methotrexate.

I was diagnosed with psoriatic arthritis just over 2 years ago and to cut a long story short I’m currently on injections of methotrexate, and since my dose has increased to the maximum 25g I’ve been getting a lot of fatigue and have put it down to the higher dose.

I’m also still getting some pain in various joints - possibly ligaments, that lasts between 3-10 days then I’ll be ok for several weeks and my blood tests have been showing up fine. Could this still be my psoriatic arthritis even though my blood results seem fine when I have my usual blood test? Has anyone else experienced this?

Have an appointment with my rheumatologist next month.

Hope everyone is well 😊
27 Jul
10:34pm, 27 Jul 2020
6654 posts
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Northern Exile
I was on 25mg at one point and concur it knocks the stuffing out of you. I've managed to get off methotrexate, it's been over a year since my last injection and I manage my condition with diet anf and the occasional naproxen.
28 Jul
11:16am, 28 Jul 2020
1806 posts
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Pinkliverbird
Thanks Northern Exile, that’s great to hear you’re off the methotrexate.
28 Jul
11:58am, 28 Jul 2020
6659 posts
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Northern Exile
I just realised I didn't really help answer your question. You need someone medically qualified to comment really, however my thoughts are that the pain is very likely to be your PsA - in my own experience, MTX didn't solve everything. I was put on sulfasalazine as well for a while and the two together really kicked the crap out of me.

I'm sorry you have to go through this, I know how you feel.
28 Jul
1:31pm, 28 Jul 2020
1807 posts
  • 0
Pinkliverbird
Thanks Northern Exile.

I’ll be seeing my rheumatologist soon so will get their opinion. I feel that Methotrexate hasn’t really settled things down for me even though my dose has increased several times over the past 18 months or so. Now that I’m on the maximum dose, hopefully they’ll change something to improve the situation.

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About This Thread

Maintained by Plodder54
I've been taking Methotrexate for Rhumatoid Arthritis since mid January. The query's I have are is...

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